- Newborns are often small and floppy.
- Male infants may have undescended testicles.
- Trouble eating as an infant, with poor weight gain
- Almond-shaped eyes
- Delayed motor development
- Narrow bifrontal skull
- Excessive intake of food due to feeling of permanent hunger
- Rapid weight gain
- Short stature
- Very small hands and feet in comparison to the child’s body.
- Sex glands produce little or no hormones
- Slow mental development.
- learning difficulties
- lack of secondary sexual development
- behavioural problems, such as temper tantrums or stubbornness
Children have an intense craving for food and will do almost anything to get it. This can result in uncontrollable weight gain and morbid obesity.
The genetic changes occur randomly.
Genetic testing is available to test children for Prader-Willi syndrome.
As the child grows older, laboratory tests may show signs of morbid obesity, such as:
Abnormal glucose tolerance
Above normal level of the hormone insulin in the blood
Decreased level of oxygen in the blood
Failure to respond to luteinizing hormone releasing factor
Heimlich manoeuvre;a procedure for managing a chocking patient, is been taught to parents or guardians of patients because they are at high risk of choking as compulsive eating abnormally expands their stomach.
There is no cure for PWS, so treatment aims to manage the symptoms and associated problems. For parents, this includes dealing with their child’s behavioural problems and excessive eating.
Limiting calories will control the obesity, but the family, neighbors, and school must work together closely because the child will try to get food wherever possible.
Improve physical strength and agility
Increase lean muscle mass and decrease body fat
Improve weight distribution
Increase bone mineral density
There have been some concerns that taking growth hormone therapy may lead to sleep apnea. A child who takes hormone therapy needs to have annual sleep studies to monitor for sleep apnea.
Low levels of sex hormones may be corrected at puberty with hormone replacement.
Type 2 diabetes
Right-sided heart failure
Bone (orthopedic) problems.
This is a terrible health condition, at first parents would ensure that their children feed well and then try to restrain them from over eating. Lastly, they do not have a long life expectancy when compared to other children.